A low detection limit penicillin biosensor based on single graphene nanosheets preadsorbed with hematein/ionic liquids/penicillinase - Details

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Abstract：

In　this　study,　we　reported　on　a　low　detection　limit　penicillin　biosensor　with　layer-by-layer　(LbL)　film　containing　single-graphene　nanosheets　(SGNs)　preadsorbed　with　hematein,　ionic　liquids　(ILs)　and　penicillinase.　The　penicillinase　catalyzes　the　hydrolysis　of　penicillin　to　penicilloic　acid,　where　H+　is　liberated　and　monitored　amperometrically　with　hematein　as　a　pH　indicator.　The　SGN-hematein/ILs/penicillinase　biosensor　exhibited　excellent　performance　for　penicillin　in　PBS　with　a　wide　range　from　1.25　×　10　-　13　to　7.5　×　10-　3　M,　and　a　low　detection　limit　of　10-　13　M　(0.04　ppt,　S/N　≥　3).　Furthermore,　the　detection　of　penicillin　concentration　in　real　sample　(milk)　had　acceptable　accuracy　with　the　assay　system.　©　2014　Elsevier　B.V.

Keyword：

Electrochemistry; Graphene nanosheets; Hematein; Ionic liquids; Penicillin biosensor

Community：

[ 1 ] [Wu, Y.]Fujian Key Lab of Medical Instrument and Pharmaceutical Technology, Yishan Campus, Fuzhou University, Fuzhou, Fujian 350002, China
[ 2 ] [Wu, Y.]Institute of Research for Functional Materials, Yishan Campus, Fuzhou University, Fuzhou, Fujian 350002, China
[ 3 ] [Wu, Y.]College of Chemistry and Chemical Engineering, Qishan Campus, Fuzhou University, Fuzhou, Fujian 350108, China
[ 4 ] [Tang, L.]Fujian Key Lab of Medical Instrument and Pharmaceutical Technology, Yishan Campus, Fuzhou University, Fuzhou, Fujian 350002, China
[ 5 ] [Tang, L.]Institute of Research for Functional Materials, Yishan Campus, Fuzhou University, Fuzhou, Fujian 350002, China
[ 6 ] [Tang, L.]College of Chemistry and Chemical Engineering, Qishan Campus, Fuzhou University, Fuzhou, Fujian 350108, China
[ 7 ] [Huang, L.]Fujian Key Lab of Medical Instrument and Pharmaceutical Technology, Yishan Campus, Fuzhou University, Fuzhou, Fujian 350002, China
[ 8 ] [Huang, L.]Institute of Research for Functional Materials, Yishan Campus, Fuzhou University, Fuzhou, Fujian 350002, China
[ 9 ] [Huang, L.]College of Chemistry and Chemical Engineering, Qishan Campus, Fuzhou University, Fuzhou, Fujian 350108, China
[ 10 ] [Han, Z.]Institute of Research for Functional Materials, Yishan Campus, Fuzhou University, Fuzhou, Fujian 350002, China
[ 11 ] [Han, Z.]College of Chemistry and Chemical Engineering, Qishan Campus, Fuzhou University, Fuzhou, Fujian 350108, China
[ 12 ] [Wang, J.]College of Chemistry and Chemical Engineering, Qishan Campus, Fuzhou University, Fuzhou, Fujian 350108, China
[ 13 ] [Pan, H.]Fujian Key Lab of Medical Instrument and Pharmaceutical Technology, Yishan Campus, Fuzhou University, Fuzhou, Fujian 350002, China
[ 14 ] [Pan, H.]Institute of Research for Functional Materials, Yishan Campus, Fuzhou University, Fuzhou, Fujian 350002, China
[ 15 ] [Pan, H.]College of Chemistry and Chemical Engineering, Qishan Campus, Fuzhou University, Fuzhou, Fujian 350108, China

Reprint 's Address：

[Pan, H.]College of Chemistry and Chemical Engineering, Qishan Campus, Fuzhou University, Fuzhou, Fujian 350108, China

Email：

hbpan@fzu.edu.cn

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Source ：

Materials Science and Engineering C

ISSN： 0928-4931

Year： 2014

Issue： 1

Volume： 39

Page： 92-99

3 . 0 8 8

JCR@2014

8 . 1 0 0

JCR@2023

JCR Journal Grade：3

CAS Journal Grade：2

Cited Count：

WoS CC Cited Count： 0

SCOPUS Cited Count： 47

ESI Highly Cited Papers on the List： 0 Unfold All

WanFang Cited Count：

Chinese Cited Count：

30 Days PV： 2

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