The　CF3S-substituted　moiety　serves　as　an　important　structural　element　in　many　bioactive　molecules.　A　versatile　copper　catalyst　that　allowed　for　trifluoromethylthiolation　of　primary　and　secondary　α-bromoketones　is　described.　The　reaction　with　readily　available　elemental　sulfur　and　CF　3SiMe3　afforded　a　broad　scope　and　moderate　to　good　yields　of　α-trifluoromethylthio-substituted　ketones.　This　procedure　represents　a　very　operationally　simple　yet　powerful　strategy　for　the　synthesis　of　α-trifluoromethylthio-substituted　ketones,　a　useful　and　versatile　class　of　synthetic　synthons.　©　2014　American　Chemical　Society.