Speradines F-H, three new oxindole alkaloids from the marine-derived fungus aspergillus oryzae - Details

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Abstract：

A　rare　hexacyclic　oxindole　alkaloid,　speradine　F　(1),　together　with　two　novel　tetracyclic　oxindole　alkaloids,　speradines　G　(2)　and　H　(3),　were　isolated　from　the　marine-derived　fungus　Aspergillus　oryzae.　Their　structures　were　determined　by　spectroscopic　methods　and　X-ray　diffraction　analysis.　This　study　is　the　first　report　on　cyclopiazonic　acid　(CPA)-type　alkaloids　with　a　hexacyclic　skeleton.　©　2014　The　Pharmaceutical　Society　of　Japan.

Keyword：

Aspergillus oryzae; Marine-derived fungus; Oxindole alkaloid; Speradine

Community：

[ 1 ] [Hu, X.]Institute of Biomedical and Pharmaceutical Technology, College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou, 350002, China
[ 2 ] [Hu, X.]School of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, China
[ 3 ] [Xia, Q.-W.]Institute of Biomedical and Pharmaceutical Technology, College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou, 350002, China
[ 4 ] [Zhao, Y.-Y.]Institute of Biomedical and Pharmaceutical Technology, College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou, 350002, China
[ 5 ] [Zheng, Q.-H.]Fujian Provincial Key Laboratory of Tumor Biotherapy, Fujian Provincial Cancer Hospital, Fuzhou, 350014, China
[ 6 ] [Liu, Q.-Y.]Fujian Provincial Key Laboratory of Tumor Biotherapy, Fujian Provincial Cancer Hospital, Fuzhou, 350014, China
[ 7 ] [Chen, L.]Institute of Biomedical and Pharmaceutical Technology, College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou, 350002, China
[ 8 ] [Zhang, Q.-Q.]Institute of Biomedical and Pharmaceutical Technology, College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou, 350002, China
[ 9 ] [Zhang, Q.-Q.]Institute of Biomedical Engineering, Chinese Academy of Medical Science, Peking Union Medical College, Tianjin, 300192, China

Reprint 's Address：

[Chen, L.]Institute of Biomedical and Pharmaceutical Technology, College of Chemistry and Chemical Engineering, Fuzhou UniversityChina

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Source ：

Chemical and Pharmaceutical Bulletin

ISSN： 0009-2363

Year： 2014

Issue： 9

Volume： 62

Page： 942-946

1 . 1 6 4

JCR@2014

1 . 5 0 0

JCR@2023

ESI HC Threshold：268

JCR Journal Grade：3

CAS Journal Grade：4

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SCOPUS Cited Count：

ESI Highly Cited Papers on the List： 0 Unfold All

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Chinese Cited Count：

30 Days PV： 2

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