A　novel　Cu@PdCu/C　catalyst　with　the　core-shell　structure　is　prepared　by　the　galvanic　replacement　between　Pd2+　ions　and　Cu　particles.　It　is　characterized　by　X-ray　diffraction　(XRD),　X-ray　photoelectron　spectroscopy　(XPS),　transmission　electron　microscopy　(TEM),　energy-dispersive　X-ray　spectra　(EDX)　and　electrochemical　measurements.　The　Cu@PdCu　nanoparticles　are　composed　of　the　Cu　core　and　PdCu　alloying　shell　with　a　thickness　of　ca.　0.5　nm.　The　peak　current　density　of　ethanol　oxidation　on　Cu@PdCu/C　is　166.0　mA　cm-2,　which　is　2.78　times　higher　than　that　on　Pd/C　catalyst　(59.8　mA　cm-2).　Durability　and　poisoning　tolerance　of　this　catalyst　are　also　greatly　improved.　©　2014　Elsevier　B.V.　All　rights　reserved.