We　reported　a　visible-light-induced　difluoroalkylation　and　cyclization　cascade　reaction　of　1,8-enynes　with　broad　substrate　scopes　in　up　to　92%　isolated　yields.　This　method　provides　a　sustainable　and　efficient　access　to　the　synthesis　of　difluoroalkylated　tetracyclic　compounds　under　mild　conditions.　©　2017　American　Chemical　Society.