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author:

Xu, H. (Xu, H..) [1] | Liang, S. (Liang, S..) [2] | Zhu, X. (Zhu, X..) [3] | Wu, X. (Wu, X..) [4] | Dong, Y. (Dong, Y..) [5] | Wu, H. (Wu, H..) [6] | Zhang, W. (Zhang, W..) [7] | Chi, Y. (Chi, Y..) [8]

Indexed by:

Scopus

Abstract:

A novel g-C3N4 nanosheets embedded with C3N4 QDs nanocomposites (QD@CNNS) was prepared by simple oxidation using hydrogen peroxide and UV light irradiation. This nanocomposite exhibits more stable and stronger electrochemiluminescent (ECL) behavior compared with CNNS. Coupling this nanocomposite with Fc-labeled aptamer, a signal-on aptasensor for platelet derived growth factor BB (PDGF-BB) is fabricated. Initially, the Fc-labeled aptamer binds onto QD@CNNS via π-π conjugation and electrostatic interaction, quenching ECL emission from QD@CNNS. The introduction of target efficiently recovers the ECL signal by the formation of PDGF-BB/aptamer complex. The ECL intensity is proportion to the concentration of PDGF-BB in the range of 0.02–80 nM with a detection limit of 0.013 nM. This work demonstrates a simple synthesis method to obtain QD@CNNS with excellent ECL behavior, and opens up the application of g-C3N4 nanocomposite in signal-on aptasensing. © 2016

Keyword:

C3N4 QDs@ C3N4 nanosheet; Electrochemiluminescent; Platelet derived growth factor BB; Signal-on aptasensor

Community:

  • [ 1 ] [Xu, H.]MOE Key Laboratory of Analysis and Detection for Food Safety, State Key Laboratory of Photo catalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fujian, 350108, China
  • [ 2 ] [Xu, H.]Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China
  • [ 3 ] [Liang, S.]Department of Environmental Science and Engineering, Fuzhou University, Minhou, Fujian 350108, China
  • [ 4 ] [Zhu, X.]College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, China
  • [ 5 ] [Wu, X.]Department of Environmental Science and Engineering, Fuzhou University, Minhou, Fujian 350108, China
  • [ 6 ] [Dong, Y.]MOE Key Laboratory of Analysis and Detection for Food Safety, State Key Laboratory of Photo catalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fujian, 350108, China
  • [ 7 ] [Wu, H.]MOE Key Laboratory of Analysis and Detection for Food Safety, State Key Laboratory of Photo catalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fujian, 350108, China
  • [ 8 ] [Zhang, W.]Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China
  • [ 9 ] [Chi, Y.]MOE Key Laboratory of Analysis and Detection for Food Safety, State Key Laboratory of Photo catalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fujian, 350108, China

Reprint 's Address:

  • [Chi, Y.]MOE Key Laboratory of Analysis and Detection for Food Safety, State Key Laboratory of Photo catalysis on Energy and Environment, College of Chemistry, Fuzhou UniversityChina

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Source :

Biosensors and Bioelectronics

ISSN: 0956-5663

Year: 2017

Volume: 92

Page: 695-701

8 . 1 7 3

JCR@2017

1 0 . 7 0 0

JCR@2023

ESI HC Threshold:226

JCR Journal Grade:1

CAS Journal Grade:1

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 0

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