The　greatly　increasing　vehicle　amount　results　in　the　increasing　probability　of　vehicles　on　bridge　while　earthquake　arises.　In　order　to　investigate　the　impact　of　moving　vehicles　on　the　seismic　response　characteristics　of　highway　continuous　girder　bridge,　a　3×40　m　continuous　T-shaped　girder　bridge　and　a　motorcade　of　super-20　were　involved　in　the　study.　Based　on　the　force　and　geometric　compatibility　condition　at　the　contact　points　of　the　vehicle-bridge　system,　a　methodology　for　analyzing　the　vehicle-bridge-earthquake　(VBE)　interaction　system　was　first　developed.　Then　the　motorcade　was　modeled　as　a　series　of　multi-DOFs　axial　loading　vehicles　incorporating　the　vehicle　dynamic　effects.　A　numerical　program　was　developed　by　APDL　language　of　ANSYS,　and　hereby　a　comprehensive　parametric　study　was　conducted　to　investigate　the　effects　of　moving　vehicular　loadings　on　the　seismic　responses　of　the　bridge　under　small　to　moderate　level　three-directional　ground　motion　input.　The　results　show　that　under　the　action　of　the　three-directional　typical　seismic　records,　the　seismic　responses　on　pier　moments　and　bearing　displacements　of　the　continuous　beam　bridge　are　significantly　influenced　by　the　moving　vehicles,　whereas　the　degree　of　impact　is　directly　related　to　the　vehicle　speed,　the　tire　stiffness　and　the　pier＇s　height.　The　longitudinal　pier　moment　and　bearing　displacement　will　decrease　as　the　number　of　lateral　loading　lanes　increase.　However　on　the　contrary,　the　concurrent　lateral　pier　moment　and　bearing　displacement　will　increase　with　increasing　of　loading　lanes,　but　the　ratio　of　change　will　decrease.　The　effects　of　moving　vehicles　on　seismic　responses　of　the　bridge　fluctuate　with　changing　of　the　vehicle　speeds　and　tandem　weights.　However　the　road　surface　roughness　has　little　impact　on　the　bridge　seismic　response.　Some　results　are　consistent　with　those　of　the　published　ones,　while　some　of　them　still　needs　further　validation　by　experiment.　©　2017,　Nanjing　Univ.　of　Aeronautics　an　Astronautics.　All　right　reserved.