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author:

Guo, L. (Guo, L..) [1] | Jackman, J.A. (Jackman, J.A..) [2] | Yang, H.-H. (Yang, H.-H..) [3] | Chen, P. (Chen, P..) [4] | Cho, N.-J. (Cho, N.-J..) [5] | Kim, D.-H. (Kim, D.-H..) [6]

Indexed by:

Scopus

Abstract:

Based on the localized surface plasmon resonance (LSPR) of metallic nanoparticles, plasmonic nanosensors have emerged as a powerful tool for biosensing applications. Many detection schemes have been developed and the field is rapidly growing to incorporate new methodologies and applications. Amidst all the ongoing research efforts, one common factor remains a key driving force: continued improvement of high-sensitivity detection. Although there are many excellent reviews available that describe the general progress of LSPR-based plasmonic biosensors, there has been limited attention to strategies for improving the sensitivity of plasmonic nanosensors. Recognizing the importance of this subject, this review highlights recent progress on different strategies used for improving the sensitivity of plasmonic nanosensors. These strategies are classified into the following three categories based on their different sensing mechanisms: (1) sensing based on target-induced local refractive index changes, (2) colorimetric sensing based on LSPR coupling, and (3) amplification of detection sensitivity based on nanoparticle growth. The basic principles and cutting-edge examples are provided for each kind of strategy, collectively forming a unifying framework to view the latest attempts to improve the sensitivity of nanoplasmonic sensors. Future trends for the fabrication of improved plasmonic nanosensors are also discussed. © 2015 The Authors. Published by Elsevier Ltd.

Keyword:

Localized surface plasmon resonance; Metallic nanoparticles; Plasmonic nanosensors; Sensitivity

Community:

  • [ 1 ] [Guo, L.]School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637457, Singapore
  • [ 2 ] [Guo, L.]Institute of Nanomedicine and Nanobiosensing, Ministry of Education Key Laboratory of Analysis and Detection Technology for Food Safety, Fuzhou University, Fuzhou, 350116, China
  • [ 3 ] [Jackman, J.A.]School of Materials Science and Engineering, Nanyang Technological University, Singapore, 639798, Singapore
  • [ 4 ] [Jackman, J.A.]Centre for Biomimetic Sensor Science, Nanyang Technological University, Singapore, 637553, Singapore
  • [ 5 ] [Yang, H.-H.]Institute of Nanomedicine and Nanobiosensing, Ministry of Education Key Laboratory of Analysis and Detection Technology for Food Safety, Fuzhou University, Fuzhou, 350116, China
  • [ 6 ] [Chen, P.]School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637457, Singapore
  • [ 7 ] [Cho, N.-J.]School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637457, Singapore
  • [ 8 ] [Cho, N.-J.]School of Materials Science and Engineering, Nanyang Technological University, Singapore, 639798, Singapore
  • [ 9 ] [Cho, N.-J.]Centre for Biomimetic Sensor Science, Nanyang Technological University, Singapore, 637553, Singapore
  • [ 10 ] [Kim, D.-H.]School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637457, Singapore

Reprint 's Address:

  • [Kim, D.-H.]School of Chemical and Biomedical Engineering, Nanyang Technological UniversitySingapore

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Source :

Nano Today

ISSN: 1748-0132

Year: 2015

Issue: 2

Volume: 10

Page: 213-239

1 3 . 1 5 7

JCR@2015

1 3 . 2 0 0

JCR@2023

ESI HC Threshold:200

JCR Journal Grade:1

CAS Journal Grade:1

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 0

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