A novel colorimetric assay for rapid detection of cysteine and Hg2+ based on gold clusters - Details

author：

Wang, Y.-W. (Wang, Y.-W..) ^[1] | Tang, S. (Tang, S..) ^[2] | Yang, H.-H. (Yang, H.-H..) ^[3] | Song, H. (Song, H..) ^[4]

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Scopus

Abstract：

Inhibition　and　recovery　of　the　catalytic　activity　of　bovine　serum　albumin-capped　gold　nanoclusters　(BSA-AuNCs)　is　observed　for　the　first　time　by　introduction　of　cysteine　and　Hg2+.　The　prepared　BSA-AuNCs　possess　highly　intrinsic　peroxidase-like　activity.　It　can　catalyze　the　oxidation　of　3,　3,　5,　5-tetramethylbenzidine　by　H2O2　to　produce　a　blue　colored　product.　Based　on　this　phenomenon,　a　new　colorimetric　assay　for　rapid,　selective　and　sensitive　detection　of　cysteine　and　Hg2+　in　aqueous　solution　has　been　demonstrated.　The　interaction　process　between　target　molecule　and　BSA-AuNCs　is　very　fast,　so　that　the　whole　test　can　be　completed　within　ten　minutes.　Moreover,　the　fabricated　colorimetric　sensor　is　simple　and　cost-effective,　without　the　need　of　nucleic　acid　based　recognition　element　and　complicated　washing,　separation　and　labeling　process,　thus　holds　great　promise　for　routine　analysis　of　cysteine　and　Hg2+　in　real　samples.　©　2015　Elsevier　B.V.　All　rights　reserved.

Keyword：

Colorimetric sensor; Cysteine; Gold clusters; Hg2+; Rapid detection

Community：

[ 1 ] [Wang, Y.-W.]College of Food Science, Fujian Agriculture and Forestry University, Fuzhou, 350002, China
[ 2 ] [Tang, S.]Department of Pharmaceutical Analysis, Faculty of Pharmacy, Fujian Medical University, Fuzhou, Fujian 350004, China
[ 3 ] [Yang, H.-H.]Key Lab of Analysis and Detection for Food Safety of MOE, Fujian Provincial Key Lab of Analysis and Detection Technology for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, 350108, China
[ 4 ] [Song, H.]College of Food Science, Fujian Agriculture and Forestry University, Fuzhou, 350002, China

Reprint 's Address：

[Yang, H.-H.]Key Lab of Analysis and Detection for Food Safety of MOE, Fujian Provincial Key Lab of Analysis and Detection Technology for Food Safety, Department of Chemistry, Fuzhou UniversityChina

Email：

hhyang@fio.org.cn

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Source ：

Talanta

ISSN： 0039-9140

Year： 2016

Volume： 146

Page： 71-74

4 . 1 6 2

JCR@2016

5 . 6 0 0

JCR@2023

ESI HC Threshold：235

JCR Journal Grade：1

CAS Journal Grade：2

Cited Count：

WoS CC Cited Count：

SCOPUS Cited Count： 64

ESI Highly Cited Papers on the List： 0 Unfold All

WanFang Cited Count：

Chinese Cited Count：

30 Days PV： 3

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