Direct visualization of sub-femtomolar circulating microRNAs in serum based on the duplex-specific nuclease-amplified oriented assembly of gold nanoparticle dimers - Details

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Abstract：

Direct　visual　detection　of　circulating　microRNAs　could　be　a　big　challenge　due　to　the　ultralow　concentration　of　microRNAs　in　real　samples.　Herein,　we　combine　the　techniques　of　nuclease　amplification　and　oriented　assembly　of　gold　nanoparticle　dimers　to　realize　visual　detection　of　microRNAs　in　human　serum　with　the　naked　eye.　©　The　Royal　Society　of　Chemistry　2016.

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[ 1 ] [Guo, L.]Institute of Nanomedicine and Nanobiosensing, Key Lab of Analysis and Detection Technology for Food Safety, MOE and Fujian Province, College of Chemistry, Fuzhou University, Fuzhou, 350116, China
[ 2 ] [Lin, Y.]Institute of Nanomedicine and Nanobiosensing, Key Lab of Analysis and Detection Technology for Food Safety, MOE and Fujian Province, College of Chemistry, Fuzhou University, Fuzhou, 350116, China
[ 3 ] [Chen, C.]Institute of Nanomedicine and Nanobiosensing, Key Lab of Analysis and Detection Technology for Food Safety, MOE and Fujian Province, College of Chemistry, Fuzhou University, Fuzhou, 350116, China
[ 4 ] [Qiu, B.]Institute of Nanomedicine and Nanobiosensing, Key Lab of Analysis and Detection Technology for Food Safety, MOE and Fujian Province, College of Chemistry, Fuzhou University, Fuzhou, 350116, China
[ 5 ] [Lin, Z.]Institute of Nanomedicine and Nanobiosensing, Key Lab of Analysis and Detection Technology for Food Safety, MOE and Fujian Province, College of Chemistry, Fuzhou University, Fuzhou, 350116, China
[ 6 ] [Chen, G.]Institute of Nanomedicine and Nanobiosensing, Key Lab of Analysis and Detection Technology for Food Safety, MOE and Fujian Province, College of Chemistry, Fuzhou University, Fuzhou, 350116, China

Reprint 's Address：

[Guo, L.]Institute of Nanomedicine and Nanobiosensing, Key Lab of Analysis and Detection Technology for Food Safety, MOE and Fujian Province, College of Chemistry, Fuzhou UniversityChina

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Chemical Communications

ISSN： 1359-7345

Year： 2016

Issue： 76

Volume： 52

Page： 11347-11350

6 . 3 1 9

JCR@2016

4 . 3 0 0

JCR@2023

ESI HC Threshold：235

JCR Journal Grade：1

CAS Journal Grade：2

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SCOPUS Cited Count： 20

ESI Highly Cited Papers on the List： 0 Unfold All

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30 Days PV： 0

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