Molecularly　imprinted　polymers　with　specific　recognition　to　salicylic　acid　(SA-MIPs)　were　prepared　by　oil-in-water　emulsion　polymerization　using　salicylic　acid　as　template,　acrylamide　as　functional　monomer,　and　ethylene　glycol　dimethacrylate　as　crosslinker.　The　morphology　and　size　distribution　of　the　SA-MIPs　were　detected　by　SEM　and　photon　cross　correlation　spectrometry.　Equilibrium　binding　experiments　and　Scatchard　analyses　were　carried　out　to　investigate　the　selectivity　of　the　SA-MIPs.　The　results　show　that　the　SA-MIPs　exhibit　a　higher　affinity　and　selectivity　to　salicylic　acid　than　to　m-hydroxybenzoic　acid　and　sulfosalicylic　acid.　Two　classes　of　binding　sites　were　produced　in　the　SA-MIPs　and　the　equilibrium　dissociation　constants　were　estimated　to　be　2.03　and　9.97　mmol/L,　respectively.　Copyright　©　2008　WILEY-VCH　Verlag　GmbH　&　Co.　KGaA.