The　UV-Visible　absorption　spectra　and　the　fluorescence　emission　spectra　of　sixteen　tetra-substituted　metallo-phthalocyanine　complexes　{R4PcM,　where　R=2-[4-(2-sulfonic　ethyl)piperazin-1-]　ethoxyl　(SPEO-),　2-(piperidin-1-yl)　ethoxyl　(PEO-);　substitution　position　at　α-position　and　β-position　of　phthalocyanine　ring;　M=Zn(II),　Ni(II),　Co(II)　and　Cu(II)}　were　measured.　The　influence　of　different　central　ion,　substituted　group　and　its　position,　as　well　as　different　solvent　on　the　Q-band　of　phthalocyanine　complex　in　its　UV-Vis　absorption　spectra　was　investigated.　The　influence　of　different　central　ion,　substituted　group　and　its　position　on　the　fluorescence　emission　spectra　was　discussed.　Some　properties　of　the　UV-Vis　absorption　spectra　such　as　the　maximum　absorption　wavelength　(λmax)　of　Q-band　and　its　molar　extinction　coefficient　(ε),　and　those　of　the　fluorescence　emission　spectra　such　as　fluorescence　quantum　yield　(ΦF),　fluorescence　lifetime　(τ)　and　excited　state　energy　(Es)　were　studied.　The　results　showed　that　the　λmax　of　Q-band　of　all　complexes　were　located　at　681-718　nm,　which　had　a　distinct　red　shift　in　contrast　with　unsubstituted　metallophthalocyanines　(669-671　nm).　All　complexes　of　R4PcM　possessed　a　very　high　molar　extinction　coefficient　up　to　105　L·mol-1·cm-1.　And　the　UV-Vis　absorption　spectra　and　the　fluorescence　emission　spectra　of　all　complexes　exhibited　mirror　shape　concurrently.　Two　β-substituted　zinc　phthalocyanine　complexes　with　formula　β-(SPEO)4PcZn　and　β-(PEO)4PcZn　possessed　very　high　molar　extinction　coefficient,　fluorescence　quantum　yield　and　fluorescence　lifetime　specially.　Therefore,　it　is　hoped　that　these　two　would　be　developing　to　be　new　photosensitizers　for　photodynamic　therapy　(PDT)　and　photodynamic　diagnosis　(PDD).