A　non-autonomous　commensal　symbiosis　model　of　two　populations　with　Michaelis-Menten　type　harvesting　is　proposed　and　studied　in　this　paper.　By　using　a　continuation　theorem　based　on　Gaines　and　Mawhin’s　coincidence　degree,　we　study　the　global　existence　of　positive　periodic　solutions　of　the　system.　By　constructing　a　suitable　Lyapuonov　function,　sufficient　conditions　which　ensure　the　global　attractivity　of　the　positive　periodic　solution　are　obtained.　Numeric　simulations　are　carried　out　to　show　the　feasibility　of　the　main　results.　©　2019　the　authors.