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author:

Yuan, W.-Q. (Yuan, W.-Q..) [1] | Zhou, S.-Q. (Zhou, S.-Q..) [2] | Jiang, Y.-Y. (Jiang, Y.-Y..) [3] | Li, H.-H. (Li, H.-H..) [4] | Zheng, H.-D. (Zheng, H.-D..) [5]

Indexed by:

Scopus

Abstract:

Considering the low conversion and long reaction time in scaling up reaction in batch reactor, the organocatalyzed epoxidation reaction of styrene was intensified under continuous flow conditions using a commercial fluidic reactor (Corning Advanced Flow G1 Reactor). After investigating the effect of reaction temperature, catalyst amount, MeCN/t-BuOH ratio, FO/FAB (buffer solution amount), total feed flow rate and operating mode on the epoxidation reaction, the optimal reaction conditions were identified under continuous flow conditions. Upon optimization, high conversion and excellent selectivity with short reaction time (3.17 min) can be obtained. We successfully developed a process for the rapid and continuous epoxidation of styrene using an organocatalyst with hydrogen peroxide as the oxidant. Compared with the batch conditions, the continuous flow reactor can exhibit unique advantages including high-speed, safety, continuousness and absence of amplifying effect, which will be significant for the industrial production of epoxides. © 2020, Akadémiai Kiadó.

Keyword:

Continuous synthesis; Epoxidation; Organocatalyst; Styrene

Community:

  • [ 1 ] [Yuan, W.-Q.]College of Chemical Engineering, Fuzhou University, Fuzhou, Fujian 350108, China
  • [ 2 ] [Zhou, S.-Q.]College of Chemical Engineering, Fuzhou University, Fuzhou, Fujian 350108, China
  • [ 3 ] [Jiang, Y.-Y.]College of Chemical Engineering, Fuzhou University, Fuzhou, Fujian 350108, China
  • [ 4 ] [Li, H.-H.]College of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China
  • [ 5 ] [Zheng, H.-D.]College of Chemical Engineering, Fuzhou University, Fuzhou, Fujian 350108, China

Reprint 's Address:

  • [Zheng, H.-D.]College of Chemical Engineering, Fuzhou UniversityChina

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Source :

Journal of Flow Chemistry

ISSN: 2062-249X

Year: 2020

Issue: 1

Volume: 10

Page: 227-234

2 . 7 8 6

JCR@2020

2 . 0 0 0

JCR@2023

ESI HC Threshold:160

JCR Journal Grade:3

CAS Journal Grade:4

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count: 10

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 1

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