Ag+-Coupled Black Phosphorus Vesicles with Emerging NIR-II Photoacoustic Imaging Performance for Cancer Immune-Dynamic Therapy and Fast Wound Healing - Details

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Abstract：

A　silver-ion-coupled　black　phosphorus　(BP)　vesicle　(BP　Ve-Ag+)　with　a　second　near　infrared　(NIR-II)　window　photoacoustic　(PA)　imaging　capability　was　firstly　constructed　to　maximize　the　potential　of　BP　quantum　dot　(QD)　in　deeper　bioimaging　and　diversified　therapy.　The　embedded　Ag+　could　improve　the　relatively　large　band　gap　of　BP　QD　via　intense　charge　coupling　based　on　theoretical　simulation　results,　subsequently　leading　to　the　enhanced　optical　absorption　capability,　accompanied　with　the　occurrence　of　the　strong　NIR-II　PA　signal.　Guiding　by　NIR-II　PA　bioimaging,　the　hidden　Ag+　could　be　precisely　released　with　the　disassembly　of　Ve　during　photodynamic　therapy　process　and　captured　by　macrophages　located　in　lesion　region　for　arousing　synergistic　cancer　photodynamic/Ag+　immunotherapy.　BP　Ve-Ag+　can　contrapuntally　kill　pathogenic　bacteria　and　accelerate　wound　healing　monitored　by　NIR-II　PA　imaging.　©　2020　Wiley-VCH　GmbH

Keyword：

black phosphorus; cancer therapy; photoacoustic imaging; second near-infrared window; wound healing

Community：

[ 1 ] [Li, Z.]MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350108, China
[ 2 ] [Fu, Q.]MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350108, China
[ 3 ] [Ye, J.]MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350108, China
[ 4 ] [Ge, X.]MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350108, China
[ 5 ] [Wang, J.]MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350108, China
[ 6 ] [Song, J.]MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350108, China
[ 7 ] [Yang, H.]MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350108, China

Reprint 's Address：

[Song, J.]MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou UniversityChina

Email：

jibinsong@fzu.edu.cn

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Source ：

Angewandte Chemie - International Edition

ISSN： 1433-7851

Year： 2020

1 5 . 3 3 6

JCR@2020

1 6 . 1 0 0

JCR@2023

ESI HC Threshold：160

JCR Journal Grade：1

CAS Journal Grade：2

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WoS CC Cited Count：

SCOPUS Cited Count： 79

ESI Highly Cited Papers on the List： 0 Unfold All

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Chinese Cited Count：

30 Days PV： 1

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