Helping　to　reconstruct　and　restore　tactile　perception　motivates　the　continuous　development　of　functional　materials,　sensing　structures,　and　manufacturing　strategies.　Coding　and　use　of　mechanotransduction　signals　from　artificial　tactile　perception　make　a　vital　contribution　to　provide　tactile　feedback　for　robots,　prosthetics,　and　rehabilitation　therapy.　Here　we　propose　a　hetero-contact　microstructure　(HeCM)　to　fabricate　tactile　sensor　by　using　silver　nanowires@polyurethane　scaffold　combined　with　layered　carbon　fabric.　The　synergistically　perceiving　of　the　HeCM　enables　the　mechanosensational　range　of　tactile　sensor　to　be　programmatically　and　significantly　enhanced　by　＞100%　compared　to　the　one　of　the　common　counterpart.　The　as-designed　sensor　characterizes　high　sensitivity,　fast　response　time,　and　reproducible　electromechanical　properties　to　identify　static　and　dynamic　external　pressure　changes.　Actual　fingertip　events　can　be　converted　into　visual　or　audio　interactive　feedback　in　virtual　reality　by　the　intelligent　sensor,　demonstrating　the　feasibility　and　practicality　of　design　concept　and　great　potential　of　the　sensor　for　human-interactive　system.　©　2019　Elsevier　Ltd