Cassava　residue　was　liquefied　by　using　ethylene　glycol　(EG),　ethylene　carbonate,　propylene　carbonate　and　polyethylene　glycol　(molecular　weight:　400　g/mol)　as　the　liquefaction　reagent　respectively　at　the　temperature　of　130–170　°C　with　sulfuric　acid　as　the　catalyst.　The　influences　of　liquefaction　parameters,　such　as　the　type　of　liquefaction　reagents,　mass　ratio　of　EG/cassava　residue,　liquefaction　temperature　and　time　on　the　properties　of　the　products　were　discussed.　The　optimum　liquefaction　conditions　were　obtained　when　the　mass　ratio　of　EG/cassava　residue　was　6:1　(w/w),　the　liquefaction　temperature　was　150　°C,　the　liquefaction　time　was　3　h　and　the　mass　fraction　of　concentrated　sulfuric　acid/EG　was　2.5wt%.　The　hydroxyl　numbers　and　residue　content　of　the　liquefied　products　at　optimal　conditions　were　1　137　mgKOH/g　and　0.43%,　respectively.　FT-IR　spectrum　showed　that　the　liquefaction　product　of　cassava　residue　was　polyether　polyol　and　could　be　used　to　prepare　polyurethane　material　or　alkyd　resins.　©　2019,　Wuhan　University　of　Technology　and　Springer-Verlag　GmbH　Germany,　Part　of　Springer　Nature.