Synthesis of high quality dual-mode encoded phenolic resin microspheres based on Fluorescence and Surface Enhanced Raman Spectra - Details

author：

You, L. (You, L..) ^[1] | Wang, A. (Wang, A..) ^[2] | Song, L. (Song, L..) ^[3] | Huang, C. (Huang, C..) ^[4] | Zhang, Q. (Zhang, Q..) ^[5]

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Abstract：

Encoded　microsphere　suspension　array　is　promising　for　multiplex　bioassay.　Novel　high　quality　phenolic　resin　(PR)　microspheres　encoded　by　Fluorescence　and　Surface　Enhanced　Raman　Spectra　(SERS)　were　fabricated　in　the　present　work.　The　PR　microspheres　possessed　autofluorescence　property　and　could　be　jointly　encoded　with　other　fluorescent　molecules　including　fluorescein　isothiocyanate.　The　fluorescent　encoded　PR　microspheres　were　modified　with　Ag　nanoparticles　and　Raman　label　molecules　for　combination　of　SERS　encoding,　which　is　rarely　reported.　The　dual-mode　encoded　microspheres　were　evaluated　by　MTT　assay　and　flow　cytometry.　The　results　showed　the　high　quality　encoded　microspheres　presented　promising　application　prospect　in　biomarker　and　detection　of　antibody,　DNA　and　RNA.　©　2017　Elsevier　B.V.

Keyword：

Encoded microspheres; Fluorescence; Polymeric composites; Raman

Community：

[ 1 ] [You, L.]Institute of Biomedical and Pharmaceutical Technology & College of Chemistry, Fuzhou University, Fuzhou, 350001, China
[ 2 ] [Wang, A.]Institute of Biomedical and Pharmaceutical Technology & College of Chemistry, Fuzhou University, Fuzhou, 350001, China
[ 3 ] [Song, L.]Institute of Biomedical and Pharmaceutical Technology & College of Chemistry, Fuzhou University, Fuzhou, 350001, China
[ 4 ] [Huang, C.]Institute of Biomedical and Pharmaceutical Technology & College of Chemistry, Fuzhou University, Fuzhou, 350001, China
[ 5 ] [Zhang, Q.]Institute of Biomedical and Pharmaceutical Technology & College of Chemistry, Fuzhou University, Fuzhou, 350001, China

Reprint 's Address：

[You, L.]Institute of Biomedical and Pharmaceutical Technology & College of Chemistry, Fuzhou UniversityChina

Email：

ibptylj@fzu.edu.cn

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Source ：

Materials Letters

ISSN： 0167-577X

Year： 2018

Volume： 212

Page： 65-68

3 . 0 1 9

JCR@2018

2 . 7 0 0

JCR@2023

ESI HC Threshold：284

JCR Journal Grade：2

CAS Journal Grade：3

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ESI Highly Cited Papers on the List： 0 Unfold All

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30 Days PV： 0

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