This　study　investigated　the　migration　law　of　ion　release　and　adsorption　in　the　flotation　pulp　of　oxide　zinc　ore,　and　found　that　numerous　different　ions　existed　in　the　pulp.　The　total　concentrations　and　major　sources　of　various　ions　(Pb2+,　Zn2+,　Fe3+,　Ca2+,　Mg2+,　SO4　2-,　etc.),　released　from　the　minerals　after　grinding,　were　determined.　The　zeta　potential　tests　indicated　that　a　mixed-ion　solution　strongly　influences　the　surface　charge　of　the　minerals.　The　flotation　tests　show　that　the　migration　law　of　ions　is　detrimental　to　the　separation　and　concentration　of　minerals.　©　2017　Taylor　&　Francis.