This　paper　presents　a　low　noise　and　residual　offset　chopper-stabilized　precision　instrumentation　amplifier　intended　for　use　in　measurement　systems.　Conventional　chopper-stabilized　instrumentation　amplifier　introduces　a　necessary　trade-off　between　the　low　residual　offset　and　noise　provided　by　a　high-transconductance　input　stage　and　the　resulting　high　residual　ripple.　However,　to　achieve　low　noise　and　residual　offset,　the　proposed　chopper-stabilized　instrumentation　amplifier　employs　a　relatively　high-transconductance　input　stage　to　reduce　the　offset　and　1/f　noise,　and　uses　a　switched-capacitor　notch　filter　as　low-pass　filter　to　filter　out　the　chopper　ripple　caused　by　the　up-modulated　offset　and　1/f　noise,　and　introduces　a　ripple　reduction　loop　(RRL)　to　reduce　the　resulting　high　residual　ripple　amplitude.　The　complete　chopper-stabilized　instrumentation　amplifier　is　implemented　in　a　standard　0.18 μm　CMOS　technology.　It　occupies　an　area　of　approximately　1.2 mm2　and　consumes　75 μA　current　from　a　1.6 V　supply　voltage.　The　input-referred　noise　power　spectral　density　is　20 nV/√Hz　and　its　residual　offset　is　less　than　4 μV.　The　RRL　achieves　a　ripple　rejection　ratio　of　26 dB.　©　2018,　Springer　Science+Business　Media,　LLC,　part　of　Springer　Nature.