The　feasibility　and　energy　saving　for　the　separation　of　tetrahydrofuran　and　water　were　studied　by　pressure　swing　distillation　and　extractive　distillation　based　on　the　characteristics　of　the　binary　azeotropic　composition.　The　above　two　techniques　were　simulated　and　optimized　by　Aspen　Plus　using　the　activity　coefficient　model　NRTL　with　binary　interaction　parameters　correlated　by　the　experimental　data　of　vapor-liquid　equilibrium.　The　results　indicate　that　the　azeotropic　mixture　of　tetrahydrofuran　and　water　can　be　effectively　separated　by　pressure　swing　distillation　or　extractive　distillation.　Tetrahydrofuran　product　meets　the　rank　of　excellent　quality　of　the　standard　GB/T　24772-2009,　and　the　heat-integrated　pressure　swing　distillation　is　more　energy　saving,　which　can　save　11.0%　of　circulating　water　and　20.3%　of　steam.　Furthermore,　it　does　not　introduce　third　components　and　is　more　suitable　for　the　separation　of　tetrahydrofuran　and　water　system,　which　provides　the　basis　for　the　design　and　energy　saving　of　the　separation　of　the　azeotropic　system.　©　2018,　Editorial　Office　of　＂CHEMICAL　ENGINEERING＂　(CHINA).　All　right　reserved.