A　simplified　3D　multi-degree-of-freedom　(MDOF)　model　for　estimation　of　seismic　response　of　reinforced　concrete　wall-frame　structures　with　uniform　stiffness　along　the　height　are　proposed　in　this　paper.　This　model　is　aimed　at　reducing　the　computation　demand　in　the　nonlinear　response　history　analysis　(RHA).　By　employing　the　continuum　technique　for　the　structure　and　adopting　the　bilinear　hysteretic　model　for　material　properties,　the　procedure　for　the　development　of　a　simplified　MDOF　model,　called　continuum　MDOF　model　is　developed.　The　proposed　continuum　MDOF　model　is　shown　to　provide　a　simple　and　efficient　for　computation　of　nonlinear　response　of　tall　wall-frame　structures.　©　(2012)　Trans　Tech　Publications,　Switzerland.