It＇s　well　known　that　curcumin　is　practically　insoluble　in　water.　Therefore,　to　improve　the　drug　dissolution　rate,　fusion　approach　was　employed　to　prepare　curcumin　solid　dispersions　(SDs)　in　the　carrier　Pluronic　F68　with　three　different　drug　loads.　The　dissolution　rate　of　curcumin　from　the　SDs　was　measured　at　simulated　gastric　fluid.　The　concentration　of　the　dissolved　drug　in　the　medium　was　determined　by　HPLC.　The　dissolution　rates　of　the　formulations　were　dependent　on　the　drug　loading　in　SDs.　92.2%　CUR　was　dissolved　in　10　min　from　the　SDs　with　8.97%　drug　load,　whereas　the　amounts　of　drug　released　were　65.8%　and　84.2%　within　120　min　from　the　SDs　with　18.9%　and　29.0%　drug　loads,　respectively.　The　Fourier　transform　infrared　spectra　indicated　hydrogen　bond　between　the　drug　and　carrier.　Furthermore,　their　physicochemical　properties　were　well　investigated　using　differential　scanning　calorimetry　and　X-ray　diffraction.　In　the　dispersions　containing　8.97%　CUR,　the　drug　was　in　the　molecular　state.　At　a　composition　of　approximately　18.9%,　CUR　was　dispersed　as　micro-fine　crystals.　These　interesting　results　indicate　that　the　physical　states　of　the　drug　in　the　carrier,　which　are　governed　by　the　drug　loading,　can　affect　the　dissolution　rate　improvement.