The　objective　of　this　paper　is　to　optimize　the　design　and　structure　of　an　airlift-driven　raceway　bioreactor　via　the　computational　fluid　dynamics　(CFD)　simulation　for　microalgae　cultivation.　The　calculated　results　showed　that　the　airlift-driven　raceway　bioreactor　had　maximum　average　velocity　when　setting　two　airlift　tubes　(of　350　mm　in　length)　in　the　middle,　furthermore　adding　the　inducing　baffle　structure.　Under　this　condition,　minimum　dead　zone　ratio　was　obtained,　which　was　advantageous　to　the　microalgae　cultivaiton.　©　(2014)　Trans　Tech　Publications,　Switzerland.