Earthquake　ground　motions　at　multiple　supports　of　large　dimensional　structures,　such　as　cable-stayed　bridges,　inevitably　vary　due　to　seismic　wave　propagation　effects.　Most　previous　studies　on　the　seismic　responses　of　cable-stayed　bridges　mainly　focused　on　the　numerical　simulations　and　the　influence　of　spatially　varying　ground　motions　were　rarely　considered.　This　paper　carries　out　shake　table　tests　to　investigate　the　seismic　responses　of　a　cable-stayed　bridge　to　spatially　varying　ground　motions　with　wave　passage　effect.　The　scale　bridge　model　with　a　length　of　12.8m　was　experimentally　tested　by　using　the　twin　shake　tables　located　in　Fuzhou　University,　China.　The　influence　of　different　apparent　wave　velocities　was　investigated　in　detail.　Experimental　results　reveal　that　ground　motion　wave　passage　effect　can　significantly　influence　the　seismic　responses　of　long　span　cable-stayed　bridges,　especially　for　vertical　response　of　girder.　The　response　of　CSB　may　be　underestimated　or　overestimated　by　neglecting　the　propagated　excitations.　©　2018　11th　National　Conference　on　Earthquake　Engineering　2018,　NCEE　2018:　Integrating　Science,　Engineering,　and　Policy.　All　rights　reserved.