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author:

Kasukurthi, Mohan Vamsi (Kasukurthi, Mohan Vamsi.) [1] | Li, Shengyu (Li, Shengyu.) [2] | Borchert, Glen M. (Borchert, Glen M..) [3] | Huang, Jingshan (Huang, Jingshan.) [4] | Zhang, Dihua (Zhang, Dihua.) [5] | Housevera, Mika (Housevera, Mika.) [6] | Huang, Yulong (Huang, Yulong.) [7] | Tan, Shaobo (Tan, Shaobo.) [8] | Ma, Bin (Ma, Bin.) [9] | Li, Dongqi (Li, Dongqi.) [10] | Benton, Ryan (Benton, Ryan.) [11] | Lin, Jingwei (Lin, Jingwei.) [12]

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EI Scopus

Abstract:

Noncoding RNAs (ncRNAs) regulate gene expression in essential cellular processes and play key roles in many human diseases. Small nucleolar RNAs (snoRNAs) are a relatively large group of ncRNAs. Many studies have identified significant alterations of different snoRNAs in prostate, breast, and lung malignancies and that many of these snoRNAs have been shown to be processed into microRNA-like molecules known as snoRNA-derived RNAs (sdRNAs). Similarly, several small RNAs have also recently been found to be excised from well characterized tRNAs to function in both normal cellular metabolism and disease. In this paper, we present a new computational methodology for the identification, analysis, and visualization of ncRNA-derived RNAs (ndRNAs) with linear time and space complexity (named SURFr for Short Uncharacterized R NA Finder). We provide the results of our algorithm's running time by analyzing several publicly available datasets and finally discuss future research directions to our work. © 2019 IEEE.

Keyword:

Bioinformatics Gene expression RNA

Community:

  • [ 1 ] [Kasukurthi, Mohan Vamsi]School of Computing, University of South Alabama, Mobile; AL, United States
  • [ 2 ] [Li, Shengyu]School of Computing, University of South Alabama, Mobile; AL, United States
  • [ 3 ] [Borchert, Glen M.]University of South Alabama, Department of Pharmacology, Mobile; AL, United States
  • [ 4 ] [Huang, Jingshan]School of Computing, University of South Alabama, Mobile; AL, United States
  • [ 5 ] [Zhang, Dihua]School of Computing, University of South Alabama, Mobile; AL, United States
  • [ 6 ] [Housevera, Mika]Sun Yat-sen University, Nephrology Department, Guangzhou, China
  • [ 7 ] [Huang, Yulong]University of South Alabama, Department of Pharmacology, Mobile; AL, United States
  • [ 8 ] [Tan, Shaobo]College of Allied Health Professions, University of South Alabama, Mobile; AL, United States
  • [ 9 ] [Ma, Bin]School of Computing, University of South Alabama, Mobile; AL, United States
  • [ 10 ] [Li, Dongqi]Qilu University of Technology, Shandong Academy of Science, Jinan, Shandong, China
  • [ 11 ] [Benton, Ryan]Ocean School, Fuzhou University, Fuzhou, China
  • [ 12 ] [Lin, Jingwei]School of Computing, University of South Alabama, Mobile; AL, United States

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Year: 2019

Page: 1504-1507

Language: English

Cited Count:

WoS CC Cited Count: 0

SCOPUS Cited Count: 3

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 2

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