Excited　state　properties,　generation　of　single-state　oxygen　and　photo-oxidation　of　amino　acid　of　axially　coordinated　silicon　naphthalocyanine　compounds　have　been　investigated.　The　results　indicate　that　the　life　of　excited　triplet　state　and　generation　of　singlet　state　oxygen　gradually　reduce　with　increase　of　push　electronic　properties　of　axially　coordinated　groups　for　different　silicon　naphthalocyanine　compounds.　Reaction　rate　of　photo-oxidation　of　amino　acid　is　dependent　on　ability　of　generation　of　singlet　state　oxygen　of　different　axially　coordinated　silicon　naphthalocyanine　compounds.　Therefore,　the　first　order　rate　constant　of　photosensitized　oxidation　of　amino　acids　gradually　reduce　with　increase　of　push　electronic　properties　of　axially　coordinated　groups.