Electrochemical behaviors of diethylstilbestrol and its application in pharmacokinetics - Details

author：

Bin, Qiu (Bin, Qiu.) ^[1] | Wei, Wang (Wei, Wang.) ^[2] | Chi, Yuwu (Chi, Yuwu.) ^[3] | Chen, Guonan (Chen, Guonan.) ^[4] Unfold

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Abstract：

The　electrochemical　behaviors　of　diethylstilbestrol　(DES)　at　a　glassy　carbon　electrode　were　investigated　by　cyclic　voltammetry,　linear　sweep　voltammetry,　and　differential　pulse　voltammetry　(DPV).　Based　on　these,　a　sensitive　and　selective　DPV　method　was　developed　for　determination　of　DES.　The　linear　response　range　of　DES　is　1.0　×　10-4-2.0　×　10　-6　mol/L　and　the　detection　limit　was　8.0　×　10-8　mol/L.　The　developed　method　has　been　used　for　the　pharmacokinetics　of　DES　in　rabbit　blood　plasma.　©　2004　Elsevier　Inc.　All　rights　reserved.

Keyword：

Blood Cyclic voltammetry Electrochemistry Glass membrane electrodes Pharmacokinetics

Community：

[ 1 ] [Bin, Qiu]Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China, China
[ 2 ] [Wei, Wang]Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China, China
[ 3 ] [Chi, Yuwu]Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China, China
[ 4 ] [Chen, Guonan]Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China, China

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Source ：

Analytical Biochemistry

ISSN： 0003-2697

Year： 2005

Issue： 2

Volume： 336

Page： 196-201

2 . 6 7

JCR@2005

2 . 6 0 0

JCR@2023

JCR Journal Grade：1

Cited Count：

WoS CC Cited Count：

SCOPUS Cited Count： 22

WanFang Cited Count：

Chinese Cited Count：

30 Days PV： 2

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