Multiple　shake　table　testing　system　(MSTS)　is　an　important　prospect　for　seismic　performance　research　in　structural　engineering,　especially　for　seismic　performance　studies　for　large　span　bridge　engineering,　lifeline　engineering,　large　mechanical　equipment,　spatial　structure　and　so　on.　Due　to　the　capability　of　multiple　earthquake　excitations,　the　methodology　and　theory　of　the　MSTS　are　different　from　that　of　single　shake　table　test.　Model　construction　and　design,　earthquake　wave　selection　and　recurrence,　experimental　process　and　earthquake　damage　analysis　were　discussed　and　the　prospective　methodology　in　using　MSTS　pointed　out.　This　serves　as　a　theoretical　foundation　for　the　methodology　of　using　MSTS　and　would　promote　the　development　of　the　theory　and　methodology　in　studying　the　seismic　performance　of　structures.