Channel　assignment　is　one　of　the　most　important　issues　in　the　multi-radio　multi-channel　wireless　mesh　networks.　An　improper　channel　assignment　may　lead　to　network　partition　or　link　failure.　In　this　paper　we　focus　on　the　channel　assignment　problem　with　the　original　topology　preservation　for　the　multi-radio　mesh　networks,　and　aim　at　minimizing　the　overall　network　interference.　We　have　formulated　an　Integer　Line　Programming　(ILP)　which　can　be　used　to　find　the　optimized　solution　for　the　channel　assignment　problem　in　small-size　network.　In　this　paper　we　also　have　developed　a　distributed　algorithm　for　the　channel　assignment　due　to　the　NP-hardness　of　the　ILP.　Extensive　simulation　results　have　demonstrated　that　our　algorithms　have　good　performance　in　both　dense　and　sparse　networks　compared　with　related　works.　The　theoretic　and　experiment　results　have　shown　that　the　proposed　algorithms　serve　as　a　practical　solution　to　the　channel　assignment　problem　in　the　multi-channel　multi-radio　wireless　mesh　networks.　©　2010　Academy　Publisher.