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author:

Liu, Wei (Liu, Wei.) [1] | Zhang, Lan (Zhang, Lan.) [2] | Fan, Liangbiao (Fan, Liangbiao.) [3] | Lin, Zian (Lin, Zian.) [4] | Cai, Yimin (Cai, Yimin.) [5] | Wei, Zhenyi (Wei, Zhenyi.) [6] | Chen, Guonan (Chen, Guonan.) [7]

Indexed by:

EI

Abstract:

In this paper, a convenient and self-assembled hollow fiber solvent-stir bar microextraction (HF-SSBME) device was developed, which could stir by itself. In the extraction process, the proposed device made the solvent ' bar' not floating at the sample solution and exposing to air while organic solvents outside hollow fiber always wrapped with donor phase solvent, which reduced the vaporization of organic solvents. This design could improve the precisions and recoveries of experiments. For evaluating the device, seven anabolic steroids (prasterone, 5α-androstane-3α, 17β-diol, methandriol, 19-norandrostenediol, androstenediol, methyltestosterone and methandienone) were used as model analytes and extraction conditions such as type and volume of organic solvents, agitation speed, extraction time, extraction temperature and salt addition were studied in detail. Under the optimum conditions (15μL toluene, 40°C, stirring at 750rpm for 30min with 1.5g sodium chloride addition in 20.0mL donor phase), the linear ranges of anabolic steroids were 0.25-200ngmL-1 with gas chromatography-mass spectrometry. The limits of detection were lower than 0.10ngmL-1. The recoveries and precisions in spiked urine and hair samples were between 73.97-93.56% and 2.18-4.47% (n=5). HF-SSBME method combined the intrinsical merits of hollow fiber with the superiority of the proposed self-stirring device which can be developed to two-phase, three-phase and in situ derivatization modes with wide prospect of application. Besides, the pedestal of this proposed device can be converted to fix stir bar in stir bar sorptive extraction (SBSE) method. © 2012 Elsevier B.V.

Keyword:

Fibers Gas chromatography Lipids Mass spectrometry Organic solvents Sodium chloride Solvent extraction

Community:

  • [ 1 ] [Liu, Wei]Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Lab. of Analysis and Detection Technology for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China
  • [ 2 ] [Liu, Wei]The Sport Science Research Center, Fuzhou University, Fuzhou, Fujian 350002, China
  • [ 3 ] [Zhang, Lan]Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Lab. of Analysis and Detection Technology for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China
  • [ 4 ] [Zhang, Lan]The Sport Science Research Center, Fuzhou University, Fuzhou, Fujian 350002, China
  • [ 5 ] [Fan, Liangbiao]Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Lab. of Analysis and Detection Technology for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China
  • [ 6 ] [Lin, Zian]Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Lab. of Analysis and Detection Technology for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China
  • [ 7 ] [Cai, Yimin]Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Lab. of Analysis and Detection Technology for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China
  • [ 8 ] [Wei, Zhenyi]Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Lab. of Analysis and Detection Technology for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China
  • [ 9 ] [Chen, Guonan]Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Lab. of Analysis and Detection Technology for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China

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Source :

Journal of Chromatography A

ISSN: 0021-9673

Year: 2012

Volume: 1233

Page: 1-7

4 . 6 1 2

JCR@2012

3 . 8 0 0

JCR@2023

JCR Journal Grade:1

CAS Journal Grade:2

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count: 38

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 0

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