The　state-of-the-art　alternating-current　light-emitting　diode　(AC-LED)　technique　suffers　from　adverse　lighting　flicker　during　each　AC　cycle.　Aiming　to　compensate　the　dimming　time　of　AC-LED,　herein,　we　report　a　novel　Mg3Y2(Ge1-xSix)3O12:Ce3+　inverse-garnet　persistent　phosphor　whose　afterglow　is　efficiently　activated　by　blue　light　with　persistent　luminescence　in　millisecond　range.　It　is　experimentally　demonstrated　that　Si　doping　tailors　the　host　bandgap,　so　that　both　the　electron　charging　and　detrapping　in　the　persistent　luminescence　process　are　optimized.　To　explore　the　origin　of　the　millisecond　afterglow,　we　performed　a　series　of　thermoluminescence　analyses,　revealing　three　types　of　continuously　distributed　traps　in　the　host.　Finally,　an　AC-LED　prototype　device　was　fabricated,　which　exhibits　the　warm　white　emission　with　a　reduced　percent　flicker　of　71.7%.　These　results　demonstrate　that　the　newly　developed　persistent　phosphor　might　be　a　promising　candidate　applicable　in　low　flickering　AC-LED　which　has　advantages　of　cheaper　price,　longer　lifetime,　and　higher　energy　utilization　efficiency.　©　2015　American　Chemical　Society.