Metal-organic　frameworks　(MOFs)　have　attracted　significant　research　attention　in　diverse　areas　due　to　their　unique　physical　and　chemical　characteristics　that　allow　their　innovative　application　in　various　research　fields.　Recently,　the　application　of　MOFs　in　heterogeneous　photocatalysis　for　water　splitting,　CO2　reduction,　and　organic　transformation　have　emerged,　aiming　at　providing　alternative　solutions　to　address　the　world-wide　energy　and　environmental　problems　by　taking　advantage　of　the　unique　porous　structure　together　with　ample　physicochemical　properties　of　the　metal　centers　and　organic　ligands　in　MOFs.　In　this　review,　the　latest　progress　in　MOF-involved　solar-to-chemical　energy　conversion　reactions　are　summarized　according　to　their　different　roles　in　the　photoredox　chemical　systems,　e.g.,　photocatalysts,　co-catalysts,　and　hosts.　The　achieved　progress　and　existing　problems　are　evaluated　and　proposed,　and　the　opportunities　and　challenges　of　MOFs　and　their　related　materials　for　their　advanced　development　in　photocatalysis　are　discussed　and　anticipated.　©　2015　Wiley-VCH　Verlag　GmbH　&　Co.　KGaA.