In　this　article,　the　authors　research　on　the　effect　of　international　mobility　of　talent　impact　on　Chinese　economic　development　based　on　nonlinear　relationship.　From　the　perspective　of　the　heterogeneity　of　human　capital,　this　article　introduces　brain　drain　into　a　production　function　and　analyzes　the　relationship　between　brain　drain　and　economic　development　of　the　home　country,　and　this　paper　draws　an　conclusion　that　moderate　brain　drain　enhance　the　economic　development　of　home　country,　but　the　unlimited　brain　drain　will　weaken　the　home　country＇s　production　capacity.　On　the　contrary,　it　will　cause　the　loss　of　economic　of　the　home　country.　On　the　other　hand,　this　article　use　Chinese　Provincial　Panel　Data　during　1997-2014　to　construct　the　indicators　of　brain　drain,　and　then　use　dynamic　semi-parametric　spatial　lag　model　to　empirical　test　the　above　inference.　And　find　that　there　is　indeed　optimal　level　of　brain　drain　in　our　country,　but　the　level　of　the　eastern　coastal　provinces　is　too　high　which　inhibit　the　economic　development　of　this　region.　Therefore,　develop　differentiated　brain　drain　policies　for　coastal　and　inland,　be　a　reasonable　guide　to　the　transnational　flow　of　talent　is　important　to　increase　China＇s　economic.　©　2016　SERSC.