Active　Pd　nanoclusters　smaller　than　1.2　nm　encapsulated　inside　the　cage　of　NH2-Uio-66(Zr)　(Pd@NH2-Uio-66(Zr))　were　prepared　via　a　double-solvent　approach　combined　with　a　photoreduction　process.　The　resultant　Pd@NH2-Uio-66(Zr)　showed　excellent　performance　for　Suzuki　coupling　reaction　under　visible-light　irradiations　as　a　result　of　the　efficient　electron　transfer　from　the　light-excited　NH2-Uio-66(Zr)　to　the　confined　Pd　nanoclusters　and　the　presence　of　large　amounts　of　catalytic　active　Pd　species.　The　successful　coupling　of　MOF-based　photocatalysis　with　metal-based　catalysis　over　metal@MOFs　is　expected　to　bring　about　vast　opportunities　for　developing　active　catalysts　for　a　variety　of　light-induced　organic　transformations　attributed　to　the　diversified　MOF　structures　and　their　tunable　characteristics.　©　2016　American　Chemical　Society.