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author:

Xu, Huifeng (Xu, Huifeng.) [1] | Liang, Shijing (Liang, Shijing.) [2] | Zhu, Xi (Zhu, Xi.) [3] | Wu, Xiuqin (Wu, Xiuqin.) [4] | Dong, Yongqiang (Dong, Yongqiang.) [5] | Wu, Haishan (Wu, Haishan.) [6] | Zhang, Wenxia (Zhang, Wenxia.) [7] | Chi, Yuwu (Chi, Yuwu.) [8]

Indexed by:

EI

Abstract:

A novel g-C3N4 nanosheets embedded with C3N4 QDs nanocomposites (QD@CNNS) was prepared by simple oxidation using hydrogen peroxide and UV light irradiation. This nanocomposite exhibits more stable and stronger electrochemiluminescent (ECL) behavior compared with CNNS. Coupling this nanocomposite with Fc-labeled aptamer, a signal-on aptasensor for platelet derived growth factor BB (PDGF-BB) is fabricated. Initially, the Fc-labeled aptamer binds onto QD@CNNS via π-π conjugation and electrostatic interaction, quenching ECL emission from QD@CNNS. The introduction of target efficiently recovers the ECL signal by the formation of PDGF-BB/aptamer complex. The ECL intensity is proportion to the concentration of PDGF-BB in the range of 0.02–80 nM with a detection limit of 0.013 nM. This work demonstrates a simple synthesis method to obtain QD@CNNS with excellent ECL behavior, and opens up the application of g-C3N4 nanocomposite in signal-on aptasensing. © 2016

Keyword:

Nanocomposites Nanosheets Platelets

Community:

  • [ 1 ] [Xu, Huifeng]MOE Key Laboratory of Analysis and Detection for Food Safety, State Key Laboratory of Photo catalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fujian; 350108, China
  • [ 2 ] [Xu, Huifeng]Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou; Fujian; 350122, China
  • [ 3 ] [Liang, Shijing]Department of Environmental Science and Engineering, Fuzhou University, Minhou; Fujian; 350108, China
  • [ 4 ] [Zhu, Xi]College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou; Fujian; 350002, China
  • [ 5 ] [Wu, Xiuqin]Department of Environmental Science and Engineering, Fuzhou University, Minhou; Fujian; 350108, China
  • [ 6 ] [Dong, Yongqiang]MOE Key Laboratory of Analysis and Detection for Food Safety, State Key Laboratory of Photo catalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fujian; 350108, China
  • [ 7 ] [Wu, Haishan]MOE Key Laboratory of Analysis and Detection for Food Safety, State Key Laboratory of Photo catalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fujian; 350108, China
  • [ 8 ] [Zhang, Wenxia]Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou; Fujian; 350122, China
  • [ 9 ] [Chi, Yuwu]MOE Key Laboratory of Analysis and Detection for Food Safety, State Key Laboratory of Photo catalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fujian; 350108, China

Reprint 's Address:

  • [chi, yuwu]moe key laboratory of analysis and detection for food safety, state key laboratory of photo catalysis on energy and environment, college of chemistry, fuzhou university, fujian; 350108, china

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Source :

Biosensors and Bioelectronics

ISSN: 0956-5663

Year: 2017

Volume: 92

Page: 695-701

8 . 1 7 3

JCR@2017

1 0 . 7 0 0

JCR@2023

ESI HC Threshold:226

JCR Journal Grade:1

CAS Journal Grade:1

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 1

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