An　expedient　strategy　for　the　synthesis　of　5-oxazole　ketones　was　developed　via　homogeneous　gold　catalysis　with　4-MeO-TEMPO　as　an　oxidant.　The　desired　5-oxazole　ketones　were　achieved　in　decent　yields　with　an　excellent　functional　group　compatibility　under　mild　conditions.　The　current　protocol　also　represents　the　first　example　for　merging　a　gold　catalyst　and　radical　chemistry　in　one-pot　synthesis　with　internal　N-propargylamides.　©　2018　American　Chemical　Society.