Focused　on　the　fluid　motion　mechanism　and　corresponding　electro-optic　response　characteristics　in　the　electrowetting　display,　a　numerical　simulation　calculation　method　is　proposed　to　calculate　the　interface　change　between　the　conductive　fluid　and　the　non-conductive　fluid　in　electrowetting　and　the　motion　of　the　fluid-liquid-solid　three-phase　contact　line　under　the　influence　of　an　externally　applied　electric　field.　The　method　is　based　on　Matlab　numerical　analysis　framework.　The　Young-Laplace　equation　is　used　to　calculate　the　change　of　interface　shape　and　the　parameters　such　as　three-phase　contact　angle　and　interface　contact　area　during　the　change　process.　The　electro-optical　response　process　of　the　pixel　is　solved　by　overall　energy　balance　equation.　The　experimental　results　show　that,　the　model　successfully　simulates　the　electrohydrodynamic　characteristics　of　the　electrowetting　display,　and　the　pixel　response　time　is　proportional　to　the　oil-water　interfacial　tension.　The　simulation　results　of　the　electro-optical　response　have　good　qualitative　consistency　with　the　experimental　data　of　the　same　reference　geometry,　which　can　be　used　to　guide　the　design　of　the　fluid　parameters　in　the　electrowetting　device,　and　it　is　important　for　realizing　the　display　of　highly　stable　electrowetting　display.　©　2019,　Science　Press.　All　right　reserved.