Construction　of　semiconductor　heterojunctions　can　effectively　accelerate　the　separation　of　photo-induced　charge　carriers　and　thereby　enhance　photocatalytic　activity.　Here,　NiSe　was　used　as　an　effective　co-catalyst　to　construct　an　active　NiSe/TiO2　heterojunction　for　improving　the　photocatalytic　H2　production　of　TiO2.　The　resultant　10%NiSe/TiO2　heterojunction　exhibited　11　times　higher　photocatalytic　H2-production　activity　than　that　of　bare　TiO2.　The　NiSe/TiO2　heterojunction　and　the　photo-reduction　of　partial　Ni2+　to　Ni0　notably　accelerated　the　separation　and　transfer　of　photo-excited　electron-hole　pairs,　and　thus　resulted　in　obvious　improvement　of　H2-evolution　activity.　This　work　holds　promise　for　the　application　of　NiSe　in　photocatalysis　as　a　high-efficiency　photocatalytic　cocatalyst.　©　2019　Hydrogen　Energy　Publications　LLC