The　crystal　structure,　electronic　structure　and　ferromagnetic　properties　of　the　transition　metals　M　(where　M=Co,　Ag)　doped　rutile　TiO2　are　studied　by　using　first-principles　calculations　based　on　the　density　functional　theory　(DFT)　and　projector　augmented　wave　(PAW)　pseudo-potentials　(PP)　method.　In　the　doped　system　M2Ti14O32,　the　two　doping　atoms　tend　to　align　along　c　axis　in　the　stablest　configuration　state.　When　M　represents　Co　atom,　the　ferromagnetic　state　is　favorable　with　magnetic　moments　of　0.99　mu　B　per　Co　atom,　while　Ag2Ti14O32　has　no　magnetic　moment.　Doping　atoms　induce　new　energy　level,　which　reduces　band　gap,　decreases　Fermi　energy　level　and　thus　considerably　affects　the　optical　absorption　and　photocatalytic　activities　of　TiO2　under　visible　light　irradiation.