This　paper　Constructed　a　new　type　of　regulation　network.　Bioinformatics　is　currently　a　popular　subject.　It　is　different　from　traditional　biology　in　the　past　and　is　a　product　of　multidisciplinary　integration.　It　contains　important　biomolecules　such　as　lncRINA,　microRNA　and　circRNA;　these　biomolecules　play　an　important　role　in　biological　processes.　They　are　interconnected　and　mutually　constrained　to　jointly　regulate　the　complex　biological　functions　of　human　beings.　According　to　the　existing　database.　such　as:　HDMM,Nlir2disease,　circRNAdisease　and　lncRNAdisease,　as　shown　by　data　that　IncRNA,　microRNA　and　circRNA　are　associated　with　disease,　Some　promote　disease,　and　some　inhibit　disease.　It　can　he　seen　that　the　progress　of　graduate　students,　especially　the　occurrence　of　diseases,　if　we　start　from　a　single　biomolecule　to　study　diseases,　we　can　not　understand　the　whole　disease.　Therefore,　it　is　necessary　to　construct　a　disease-related　lncRNA-circRNA-microRNA　network,　and　it　also　has　important　guiding　significance　for　researching　disease　research.