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author:

Cai, Shaojin (Cai, Shaojin.) [1] | Xue, Yuyang (Xue, Yuyang.) [2] | Gao, Qinquan (Gao, Qinquan.) [3] (Scholars:高钦泉) | Du, Min (Du, Min.) [4] | Chen, Gang (Chen, Gang.) [5] | Zhang, Hejun (Zhang, Hejun.) [6] | Tong, Tong (Tong, Tong.) [7] (Scholars:童同)

Indexed by:

CPCI-S EI Scopus

Abstract:

Digitized pathological diagnosis has been in increasing demand recently. It is well known that color information is critical to the automatic and visual analysis of pathological slides. However, the color variations due to various factors not only have negative impact on pathologist's diagnosis, but also will reduce the robustness of the algorithms. The factors that cause the color differences are not only in the process of making the slices, but also in the process of digitization. Different strategies have been proposed to alleviate the color variations. Most of such techniques rely on collecting color statistics to perform color matching across images and highly dependent on a reference template slide. Since the pathological slides between hospitals are usually unpaired, these methods do not yield good matching results. In this work, we propose a novel network that we refer to as Transitive Adversarial Networks (TAN) to transfer the color information among slides from different hospitals or centers. It is not necessary for an expert to pick a representative reference slide in the proposed TAN method. We compare the proposed method with the state-of-the-art methods quantitatively and qualitatively. Compared with the state-of-the-art methods, our method yields an improvement of 0.87 dB in terms of PSNR, demonstrating the effectiveness of the proposed TAN method in stain style transfer.

Keyword:

Color transfer Generative adversarial networks Pathological slides Stain transfer

Community:

  • [ 1 ] [Cai, Shaojin]Fuzhou Univ, Coll Phys & Informat Engn, Fuzhou, Peoples R China
  • [ 2 ] [Gao, Qinquan]Fuzhou Univ, Coll Phys & Informat Engn, Fuzhou, Peoples R China
  • [ 3 ] [Du, Min]Fuzhou Univ, Coll Phys & Informat Engn, Fuzhou, Peoples R China
  • [ 4 ] [Tong, Tong]Fuzhou Univ, Coll Phys & Informat Engn, Fuzhou, Peoples R China
  • [ 5 ] [Cai, Shaojin]Fujian Key Lab Med Instrumentat & Pharmaceut Tech, Fuzhou, Peoples R China
  • [ 6 ] [Gao, Qinquan]Fujian Key Lab Med Instrumentat & Pharmaceut Tech, Fuzhou, Peoples R China
  • [ 7 ] [Du, Min]Fujian Key Lab Med Instrumentat & Pharmaceut Tech, Fuzhou, Peoples R China
  • [ 8 ] [Tong, Tong]Fujian Key Lab Med Instrumentat & Pharmaceut Tech, Fuzhou, Peoples R China
  • [ 9 ] [Xue, Yuyang]Imperial Vis Technol, Fuzhou, Peoples R China
  • [ 10 ] [Gao, Qinquan]Imperial Vis Technol, Fuzhou, Peoples R China
  • [ 11 ] [Tong, Tong]Imperial Vis Technol, Fuzhou, Peoples R China
  • [ 12 ] [Chen, Gang]Fujian Med Univ, Affiliated Hosp, Dept Pathol, Fujian Prov Canc Hosp, Fuzhou, Peoples R China
  • [ 13 ] [Zhang, Hejun]Fujian Med Univ, Affiliated Hosp, Dept Pathol, Fujian Prov Canc Hosp, Fuzhou, Peoples R China

Reprint 's Address:

  • 童同

    [Tong, Tong]Fuzhou Univ, Coll Phys & Informat Engn, Fuzhou, Peoples R China;;[Tong, Tong]Fujian Key Lab Med Instrumentat & Pharmaceut Tech, Fuzhou, Peoples R China;;[Tong, Tong]Imperial Vis Technol, Fuzhou, Peoples R China

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Source :

MACHINE LEARNING FOR MEDICAL IMAGE RECONSTRUCTION, MLMIR 2019

ISSN: 0302-9743

Year: 2019

Volume: 11905

Page: 163-172

Language: English

0 . 4 0 2

JCR@2005

Cited Count:

WoS CC Cited Count: 9

SCOPUS Cited Count: 13

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 2

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