The　unique　structure　of　basal　planes　and　edges　in　graphene　endows　graphene　specific　properties,　such　as　the　much　higher　heterogeneous　electron　transfer　rate,　capacitance,　local　density　of　states　and　structural　defects,　functional　groups　of　edges　than　basal　planes.　These　inherent　features　of　graphene,　which　have　a　great　role　in　promoting　its　electrochemical　performance,　are　the　embodiment　of　the　edge　effect.　This　paper　introduces　the　influence　of　edge　effect　on　the　electrochemical　performance　of　graphene,　gives　a　review　and　prospect　of　graphene　with　different　morphology　characteristics,　such　as　graphene　nanoflakes,　nanosheets,　nanoplatelets,　nanowalls,　nanofibers,　nanoribbons,　and　quantum　dots,　applying　in　the　electrochemical　biosensing　field.