We　demonstrate　the　first　observation　of　stimulated　Brillouin　scattering　(SBS)　in　a　high-Q　whispering　gallery　mode　tellurite　microsphere.　Tellurite　glass　with　composition　of　70TeO(2)-20ZnO-5Na(2)O-5La(2)O(3)　(molar　ratio)　was　prepared　in-house　using　a　melt-quenching　technique.　Moreover,　tellurite　microspheres　with　Q　in　excess　of　13　millions　at　1550　nm　were　fabricated　by　melting　tellurite　microwires　using　a　CO2　laser.　By　pumping　the　tellurite　microspheres　with　a　tunable　single　frequency　laser,　SBS　is　further　realized　with　a　threshold　as　low　as　0.58　mW.　At　last,　the　beat　notes　between　the　pump　and　the　Stokes　signals　were　measured,　which　indicated　the　Brillouin　frequency　shift　is　at　the　8.2　GHz　band　for　our　tellurite　glass.　Our　results　could　propel　significant　applications　utilizing　SBS　by　employing　tellurite　microspheres.　(C)　2015　Optical　Society　of　America