The　heterojunction　of　cadmium　sulfide　(CdS)/La2Ti2O7　(CdS/LTO)　attracts　great　attention　in　the　application　of　photocatalysis.　Here,　it　is　used　as　a　visible　light-activated　support　and　extends　to　the　application　of　direct　methanol　fuel　cells　(DMFCs).　First,　uniform　CdS　quantum　dots　(QDs)　are　deposited　on　the　surface　of　2D　perovskite-type　LTO　nanosheets　to　form　the　CdS　QDs/LTO　heterojunction.　Then,　Pt　electrocatalysts　are　deposited　on　the　as-prepared　CdS　QDs/LTO　heterojunction　and　used　as　a　working　electrode　for　the　application　of　the　methanol　oxidation　reaction　(MOR).　With　the　assistance　of　visible　light　irradiation,　the　as-prepared　electrode　shows　2.2　times　enhanced　activity　toward　MOR　than　that　under　the　dark　condition.　Moreover,　compared　to　Pt　on　the　surface　of　LTO,　the　introduced　CdS　QDs　not　only　improve　the　electrode＇s　visible　light　response,　but　also　facilitate　charge　separation　via　a　type　II　heterojunction　structure.　This　work　provides　a　new　insight　into　the　development　of　highly　efficient　CdS/La2Ti2O7　for　applications　in　DMFCs　and　beyond.