The　purple　membrane　(PM)　isolated　from　the　bacteria　Halobacterium　salinarum　(H.　salinarum)　arranges　the　transmembrane　proton　pump　bacteriorhodopsin　(bR)　in　a　2D　hexagonal　crystalline　lattice.　Here,　PM　sheets　containing　native　bR　bend　into　tube-like　structures　with　open　edges　under　acidic　pH　conditions.　When　decorated　with　gold　nanoparticles　(AuNPs),　these　same　PM　sheets　yield　a　sealed　tube　assembly.　Upon　Rhodamine　B　(Rh　B)　sequestration　inside　the　sealed　tube,　a　dramatic　decrease　in　Rh　B　fluorescence　lifetime　(tau(f))　from　1.5　ns　(unencapsulated)　to　14　ps　(encapsulated)　is　observed.　The　dramatic　decrease　in　lifetime　is　attributed　to　energy　transfer　between　AuNPs　and　Rh　B.　Subsequent　release　from　the　AuNP-PM　capsules　triggered　by　an　increase　in　pH　shows　that　93%　of　Rh　B　is　recovered　(tau　=　14　min)　due　to　the　capsules＇　unfolding.　The　hybrid　AuNP-PM　material　highlights　the　utility　of　multicomponent　ensembles　(i.e.,　lipid　bilayer,　protein　array,　and　NPs)　by　demonstrating　that　complex,　multistimuli　3D　responses　can　lead　to　multiplexed　functions　such　as　controlling　energy　transfer　in　the　confined,　encapsulated　state　and　breaking　the　energy　pair　via　molecular　release　in　response　to　a　change　in　pH.