Eco-friendly　BaTiO3　(BTO)-based　materials　have　been　intensively　studied　as　efficient　piezo-photocatalysts　for　the　degradation　of　contaminants　and　water　remediation.　However,　studies　on　pure　BTO　are　limited　due　to　weak　light　absorption,　insufficient　piezoelectric　polarization,　and　poor　catalytic　performance.　Herein,　we　used　different　liquid-phase　methods　to　prepare　pure　BTO　particles　to　enhance　the　piezo-photocatalytic　performance　through　microstructural　manipulation.　Compared　with　the　BTO　prepared　via　the　hydrothermal　method　(BTO-HT),　the　BTO-SG　(prepared　via　the　sol-gel　method)　exhibit　smaller　particles,　larger　specific　surface　area,　greater　concentration　of　oxygen　vacancies,　and　larger　bandgap　energy,　resulting　in　more　active　sites,　stronger　piezo-photocatalytic　ability,　improved　degradation　performance　for　rhodamine　B　(97　%　within　60　min)　with　a　higher　degradation　rate　constant　(5.541　×　10−2　min−1)　7.96　times　that　of　the　BTO-HT.　The　catalytic　performance　of　BTO-SG　is　superior　to　that　of　most　previously　reported　BTO-based　catalysts.　Importantly,　synergistic　piezo-photocatalysis　is　much　better　than　single　photocatalysis　(k　=　0.757　×　10−2　min−1)　or　piezocatalysis　(k　=　1.703　×　10−2　min−1).　In　addition,　the　BTO-SG　particles　maintained　stable　degradation　performance　in　environments　containing　inorganic　anions　or　with　various　pH　values.　The　degradation　mechanism　of　BTO-SG　was　proposed　in　combination　with　free　radical　detection　and　photoelectric　tests.　This　study　provides　a　design　thought　for　exploring　other　highly　efficient　BTO-based　piezo-photocatalysts　for　water　environment　treatment.　©　2024　Elsevier　Ltd　and　Techna　Group　S.r.l.